Products

Vaginal films are products designed to dissolve after being inserted in the vagina. The monthly dapivirine vaginal film is the first film designed to dissolve over the course of one month, during which time it would slowly release the antiretroviral drug dapivirine. The film is being developed by researchers at the University of Pittsburgh School of Pharmacy and Magee-Womens Research Institute.

The dual-purpose vaginal film is designed so that when placed inside the vagina, it would slowly begin to dissolve, and in doing so, release the antiretroviral drug dapivirine and a synthetic hormone called progestogen that mimics progesterone. The dual-purpose film is being developed by researchers at the University of Pittsburgh School of Pharmacy and Magee-Womens Research Institute.  

The non-ARV/non-hormonal monthly dual-purpose vaginal ring, which is sometimes called the OneRing, is being developed by the Oak Crest Institute of Science and contains two novel agents: an antiviral peptide and a soluble Adenylyl Cyclase (sAC) inhibitor that inhibits movement of sperm. 

The TAF/EVG fast-dissolving vaginal insert is an on-demand HIV prevention product. The insert, which resembles a bullet-shaped tablet, contains the antiretroviral drugs tenofovir alafenamide (TAF) and elvitegravir (EVG) and is being developed by CONRAD, a nonprofit research organization affiliated with Eastern Virginia Medical School of Old Dominion University in Norfolk, Va.